1114546-30-3

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-2-fluoro-3-methylbenzonitrile is used as a key intermediate in the synthesis of various biologically active compounds. Its unique structure and reactivity contribute to the development of new pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Bromo-2-fluoro-3-methylbenzonitrile serves as an essential intermediate for the production of agrochemicals, including pesticides and herbicides. Its properties allow for the creation of compounds that can effectively control pests and weeds in agricultural settings.
Used in Medicinal Chemistry Research:
4-Bromo-2-fluoro-3-methylbenzonitrile is utilized in medicinal chemistry research for the exploration of its potential as a precursor to new drug candidates. Its chemical properties make it a valuable tool in the design and synthesis of novel therapeutic agents.
Used in Material Science Research:
4-Bromo-2-fluoro-3-methylbenzonitrile is also used in material science research to investigate its potential applications in the development of new materials with specific properties, such as those with unique electronic, optical, or mechanical characteristics.
It is important to handle and store 4-Bromo-2-fluoro-3-methylbenzonitrile with caution, as it may pose health and environmental risks if not managed properly. Proper safety measures should be taken to minimize any potential hazards associated with its use.

Upstream product

• 1114546-29-0 1-bromo-3-fluoro-4-iodo-2-methylbenzene 
• 557-21-1 dicyanozinc 
• 105942-08-3 4-bromo-6-fluorobenzonitrile 
• 74-88-4 methyl iodide 
• 757247-93-1 4-Amino-2-fluoro-3-methylbenzonitrile 

Downstream Products

• 1114546-31-4 4-[(2S,3S)-3-(tert-butyldimethylsilyloxy)-2-methyl-5-oxopyrrolidin-1-yl]-2-fluoro-3-methylbenzonitrile 
• 1228014-43-4 4-bromo-2-fluoro-3-methylbenzamide 
• 1255207-50-1 4-bromo-3-methyl-2-(methyloxy)benzonitrile 
• 1618648-16-0 4-bromo-2-fluoro-3,5-dimethylbenzonitrile 

Relevant academic research and scientific papers

PLASMA KALLIKREIN INHIBITORS AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

BENZYLAMINE DERIVATIVES

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R1 to R3, R5 to R9, A, P, V, W, X, Y and Z are as defined herein.

MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY

Provided herein are Heteroaryl Compounds having the following structure: R2 N (I) or (II) wherein R1 -R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

This invention relates to compounds having structural Formula I: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds of Formula I are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure

Cyclic amine compounds

The present invention relates to pharmaceutical agents which are agents for the prophylaxis or treatment of hypogonadism, male climacteric disorder, frailty, cachexia or osteoporosis; the pharmaceutical agents frailty suppressants, muscle strength enhance