1114560-76-7 Usage
General Description
4-Bromo-2-methylpyrimidine is a chemical compound with the molecular formula C5H5BrN2. It is a pyrimidine derivative and contains a bromine atom and a methyl group attached to the pyrimidine ring. 4-Bromo-2-methylpyrimidine is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as an intermediate in the production of other organic compounds. 4-Bromo-2-methylpyrimidine has potential applications in the field of medicinal chemistry and is actively researched for its biological activity and potential therapeutic uses. It is important to handle this compound with caution due to its potential health hazards and harmful effects if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 1114560-76-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,4,5,6 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1114560-76:
(9*1)+(8*1)+(7*1)+(6*4)+(5*5)+(4*6)+(3*0)+(2*7)+(1*6)=117
117 % 10 = 7
So 1114560-76-7 is a valid CAS Registry Number.
1114560-76-7Relevant articles and documents
A method for preparing 2, 4 - substituted pyrimidine
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Paragraph 0010; 0018-0019, (2019/06/05)
The invention belongs to the technical field of the synthesized compounds, in particular to a 2, 4 - substituted pyrimidine of the preparation method. The method comprises the following steps: 1) the 2 - substituted pyrimidine dissolved in tetrahydrofuran, in - 60 — - 78 °C lower dropping TMP.MgCl.LiCl, dropping 1 h after adding anhydrous zinc chloride, raising the temperature to room temperature, dropping halogen, 2 h after adding hydrochloric acid solution quenching reaction; 2) reaction of the reaction solution in order to ethyl acetate extraction, drying of the organic layer concentrated, column chromatography purification to obtain the product. The invention compared with the prior art, in order to 2 - substituted pyrimidines as raw materials can be specific selection 4 substituted, at the same time does not produce 5 substituted by-product, with good selectivity, single product, is easy to be purified, with mild reaction conditions, the reaction speed and the like.
