1114592-07-2

Upstream product

• 1114592-06-1 methyl 2-chloro-6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidine-4-carboxylate 
• 99175-39-0 cyclohexyl-cyclopropylmethyl-amine; hydrochloride 
• 6299-85-0 2,6-dichloropyrimidine-4-carboxylic acid methyl ester 

Downstream Products

• 1114592-08-3 6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidine-4-carboxylic acid 
• 1114592-19-6 6-[cyclohexyl(cyclopropylmethyl)amino]-N-(4-formylphenyl)pyrimidine-4-carboxamide 
• 1114591-93-3 6-[cyclohexyl(cyclopropylmethyl)amino]-N-[4-(hydroxymethyl)phenyl]pyrimidine-4-carboxamide 
• 1114591-64-8 6-[cyclohexyl(cyclopropylmethyl)amino]-N-1H-indol-4-ylpyrimidine-4-carboxamide 
• 1114591-65-9 6-[cyclohexyl(cyclopropylmethyl)amino]-N-1H-indazol-4-ylpyrimidine-4-carboxamide 
• 1114591-75-1 6-[cyclohexyl(cyclopropylmethyl)amino]-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidine-4-carboxamide 
• 1114591-74-0 6-[cyclohexyl(cyclopropylmethyl)amino]-N-[4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl]pyrimidine-4-carboxamide 
• 1114591-15-9 N-{4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}qlycine 
• 1114591-08-0 tert-butyl N-{4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}qlycinate 
• 1114591-71-7 3-({4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}sulfonyl)propanoic acid 
• 1114591-70-6 4-({4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]phenyl}sulfonyl)butanoic acid 
• 1114591-69-3 ethyl 4-({4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]phenyl}sulfonyl)butanoate 
• 1114591-68-2 ethyl 3-({4-[({6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}sulfonyl)propanoate 

Relevant academic research and scientific papers

6-AMINO-PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS WHICH BIND TO THE SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR FOR THE TREATMENT OF MULTIPLE SCLEROSIS

The invention relates to compounds of formula (I): wherein X, W, Q, R, R1 and R2 have the meanings given in claim 1. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis.