1114592-96-9Relevant academic research and scientific papers
Synthesis of pharmacologically active apomorphines by direct N-substitution on the aporphine backbone
Sipos, Attila,Berényi, Sándor
body text, p. 1703 - 1705 (2009/05/11)
A method has been developed for the direct N-substitution of aporphines comprising the N-oxidation-N-deprotection-N-alkylation sequence. This methodology was found to be insensitive to the change in the substitution pattern of rings A or D, therefore it is presumed to be applicable also for aporphines derived from total synthesis and natural sources. Thieme Stuttgart.
