111468-05-4Relevant articles and documents
Gene Disruption and Biochemical Characterization of Verruculogen Synthase of Aspergillus fumigatus
Kato, Naoki,Suzuki, Hirokazu,Takagi, Hiroshi,Uramoto, Masakazu,Takahashi, Shunji,Osada, Hiroyuki
experimental part, p. 711 - 714 (2012/01/14)
Three in one: Verruculogen synthase FtmF is a key enzyme to diversify the fumitremorgin biosynthetic pathway in Aspergillus fumigatus: FtmF catalyzes not only endoperoxide bond formation of verruculogen but also the deprenylation and oxidation of fumitremorgin B to yield 12α,13α-dihydroxyfumitremorgin C and 13-oxoverruculogen, respectively.