111468-91-8 Usage
Uses
Given the provided materials, specific uses for 1-[5-(2,2,2-TRICHLOROACETYL)-1H-PYRROL-3-YL]-1-BUTANONE are not explicitly mentioned. However, based on its chemical structure and the general properties of pyrroles and trichloroacetic acid derivatives, potential applications could include:
Used in Pharmaceutical Industry:
1-[5-(2,2,2-TRICHLOROACETYL)-1H-PYRROL-3-YL]-1-BUTANONE could be used as a pharmaceutical intermediate for the synthesis of drugs targeting specific biological pathways or receptors, given its unique molecular structure and the potential for chemical modification.
Used in Chemical Research:
In the field of chemical research, 1-[5-(2,2,2-TRICHLOROACETYL)-1H-PYRROL-3-YL]-1-BUTANONE may serve as a model compound for studying the reactivity and properties of pyrrole and trichloroacetic acid derivatives, contributing to the development of new synthetic methods or understanding of chemical behavior.
Used in Material Science:
1-[5-(2,2,2-TRICHLOROACETYL)-1H-PYRROL-3-YL]-1-BUTANONE might also find applications in material science, potentially serving as a component in the development of new materials with specific properties, such as conductivity, stability, or reactivity, due to its aromatic and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 111468-91-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,4,6 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 111468-91:
(8*1)+(7*1)+(6*1)+(5*4)+(4*6)+(3*8)+(2*9)+(1*1)=108
108 % 10 = 8
So 111468-91-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H10Cl3NO2/c1-2-3-8(15)6-4-7(14-5-6)9(16)10(11,12)13/h4-5,14H,2-3H2,1H3
111468-91-8Relevant academic research and scientific papers
β-Acylation of ethyl pyrrole-2-carboxylate by Friedel-Crafts acylation: Scope and limitations (synthetic studies on indoles and related compounds. XXXVIII
Tani,Ariyasu,Nishiyama,Hagiwara,Watanabe,Yokoyama,Murakami
, p. 48 - 54 (2007/10/03)
The Friedel-Crafts acylation of ethyl pyrrole-2-carboxylate (3) was studied under several conditions using various Lewis acids and acyl chlorides. The acylation with various acyl chlorides in the presence of aluminum chloride gave exclusively ethyl 4-acylpyrrole-2-carboxylate (5), whereas weaker Lewis acids such as zinc chloride and boron trifluoride etherate gave a mixture of ethyl 4- and 5-acylpyrrole-2-carboxylates.
Synthesis of 2-Alkylputrescines from 3-Alkylpyrroles
Garrido, Daniel O. A.,Buldain, Graciela,Ojea, Maria I.,Frydman, Benjamin
, p. 403 - 407 (2007/10/02)
Acylation of 2-(trichloroacetyl)pyrrole gave the 4-acyl derivatives (from 4-formyl to 4-hexanoyl) in good yields.Alkaline treatment gave corresponding 4-acyl-2-pyrrolecarboxylic acids, were decarboxylated to the 3-acylpyrroles by prior conversion to the 3-acyl-2,4,5-triiodopyrroles followed by hydrogenolysis.The 3-acylpyrroles were reduced by treatment with hydrazine in alkaline medium to the 3-alkylpyrroles.The latter were ring-opened by treatment with hydroxylamine in the presence of bicarbonate to give the dioximes of the corresponding 2-alkylsuccinaldehydes, which were then reduced to the 2-alkylpurescines (1,4-diaminobutanes).Ring-opening of 2,3-dimethylpyrrole followed by reduction of the dioxime gave 1,2-dimethylputrescine; the same sequence gave 1,3-dimethylputrescine from 2,4-dimethylpyrrole, while 3,4-dimethylpyrrole did not ring-open and gave the dioxime of 3,4-dimethylmaleimide.
