111468-94-1 Usage
General Description
4-PROPIONYL-1H-PYRROLE-2-CARBOXYLIC ACID is a chemical compound with the molecular formula C8H9NO3. It is a substituted pyrrole derivative containing a propionyl group and a carboxylic acid functional group. 4-PROPIONYL-1H-PYRROLE-2-CARBOXYLIC ACID is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has applications in the pharmaceutical industry as a precursor for the synthesis of potential drug candidates. Additionally, it can be used as a building block in organic synthesis and medicinal chemistry. This chemical compound is an important intermediate for the production of various biologically active compounds and is of interest to researchers and drug developers.
Check Digit Verification of cas no
The CAS Registry Mumber 111468-94-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,4,6 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 111468-94:
(8*1)+(7*1)+(6*1)+(5*4)+(4*6)+(3*8)+(2*9)+(1*4)=111
111 % 10 = 1
So 111468-94-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3/c1-2-7(10)5-3-6(8(11)12)9-4-5/h3-4,9H,2H2,1H3,(H,11,12)/p-1
111468-94-1Relevant articles and documents
Synthesis of 2-Alkylputrescines from 3-Alkylpyrroles
Garrido, Daniel O. A.,Buldain, Graciela,Ojea, Maria I.,Frydman, Benjamin
, p. 403 - 407 (2007/10/02)
Acylation of 2-(trichloroacetyl)pyrrole gave the 4-acyl derivatives (from 4-formyl to 4-hexanoyl) in good yields.Alkaline treatment gave corresponding 4-acyl-2-pyrrolecarboxylic acids, were decarboxylated to the 3-acylpyrroles by prior conversion to the 3-acyl-2,4,5-triiodopyrroles followed by hydrogenolysis.The 3-acylpyrroles were reduced by treatment with hydrazine in alkaline medium to the 3-alkylpyrroles.The latter were ring-opened by treatment with hydroxylamine in the presence of bicarbonate to give the dioximes of the corresponding 2-alkylsuccinaldehydes, which were then reduced to the 2-alkylpurescines (1,4-diaminobutanes).Ring-opening of 2,3-dimethylpyrrole followed by reduction of the dioxime gave 1,2-dimethylputrescine; the same sequence gave 1,3-dimethylputrescine from 2,4-dimethylpyrrole, while 3,4-dimethylpyrrole did not ring-open and gave the dioxime of 3,4-dimethylmaleimide.
