111477-43-1

Basic information

• Product Name: Propanamide, N-[6-(bromomethyl)-2-pyridinyl]-2,2-dimethyl-
• CAS NO: 111477-43-1
• Molecular Formula: C11H15BrN2O
• Molecular Weight: 271.157
• Mol File: 111477-43-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanamide, N-[6-(bromomethyl)-2-pyridinyl]-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-[6-(bromomethyl)-2-pyridinyl]-2,2-dimethyl-(111477-43-1)
• EPA Substance Registry System: Propanamide, N-[6-(bromomethyl)-2-pyridinyl]-2,2-dimethyl-(111477-43-1)

Safety Data

• Hazardous Substances Data: 111477-43-1(Hazardous Substances Data)

Upstream product

• 86847-79-2 2,2-dimethyl-N-(6-methylpyridin-2-yl)propanamide 

Downstream Products

• 79651-64-2 (6-Amino-pyridin-2-yl)-methanol 
• 165685-25-6 2-(N-pivaloylamino)-6-hydroxymethylpyridine 
• 858343-58-5 N-benzyl-N-((6-pivaloylamido-2-pyridyl)methyl)-N-(2-pyridyl-methyl)amine 
• 847654-13-1 N,N-bis[(6-phenyl-2-pyridyl)methyl]-N-[(6-pivaloylamido-2-pyridyl)methyl]amine 
• 1265139-79-4 N,N'-(6,6'-(2-nitrophenylsulfonylazanediyl)bis(methylene)bis(pyridine-6,2-diyl))bis(2,2-dimethylpropanamide) 
• 1256730-35-4 bis[N-(6-pivalamidopyridin-2-ylmethyl)]benzylamine 
• 1258528-12-9 C₅₂H₆₈N₁₀O₄ 
• 167298-54-6 6-amino-2-pyridinemethanamine 
• 1449758-80-8 1-benzoyl-3-{6-[(bis-pyridin-2-ylmethylamino)-methyl]-pyridin-2-yl}-thiourea 
• 1560980-28-0 C₃₂H₃₄N₆OS 
• 1609162-86-8 C₄₄H₄₂N₆OS 

Relevant articles and documents

Side chain bromination of mono and dimethyl heteroaromatic and aromatic compounds by solid phase N-bromosuccinimide reaction without radical initiator under microwave

A series of side chain mono and dibromo derivatives of mono and dimethyl heteroaromatic and aromatic compounds (1-17) were synthesized by one step solid phase N-bromosuccinimide (NBS) reaction without radical initiator by microwave irradiation. The benzylic mono and dibromo products were exclusively preferred except in the case of 6-methylpyridine amides (8 and 9) where nuclear and also side chain bromination resulted. Naphthyridine systems resulted improved yields. By this method, we also report the synthesis of 2-pivaloylaminopterin-6- carbaldehyde.

Ethylene spacer-linked bis-acetamidopyridine for dicarboxylic acid recognition and polymeric new wave-like anti-perpendicular arrangement of a host-guest in the solid state

In this paper, 1,2-bis(2-acetamido-6-pyridyl)ethane, receptor 1, having an ethylene spacer is reported to recognise dicarboxylic acids. The binding study in the solution phase is carried out using 1H NMR (1:1) and UV-vis experiments and in the solid phase by single-crystal X-ray analysis. In 1H NMR, the downfield shifts of specific amide protons of receptor 1 in 1:1 complexes of receptor and guest diacids, and in the UV-vis experiment, the appearance of an isosbestic point as well as significant binding constants are observed, which thus unambiguously support the complexation of receptor 1 with dicarboxylic acids in solution. Receptor 2, simple 2-acetamido-6-methylpyridine, has lower binding constants than receptor 1 due to cooperative binding of two pyridine amide groups with two acid groups of diacids. In the solid phase, the ditopic receptor 1 shows a grid-like polymeric hydrogen-bonded network that changes to a polymeric wave-like 1:1 anti-perpendicular network instead of the syn-syn polymeric 1:1 (Goswami, S.; Dey, S.; Fun, H.-K.; Anjum, S.; Rahman, A.-U. Tetrahedron Lett. 2005, 46, 7187-7191), anti-anti polymeric 1:1 (Goswami, S.; Jana, S.; Dey, S.; Razak, I.A.; Fun, H.-K. Supramol. Chem. 2006, 18, 571-574; Goswami, S.; Jana, S.; Fun, H.-K. Cryst. Eng. Comm. 2008, 10, 507-517; Goswami, S.; Jana, S.; Dey, S.; Sen, D.; Fun, H.-K.; Chantrapromma, S. Tetrahedron 2008, 64, 6426-6433), syn-syn 2:2 (Karle, I.L.; Ranganathan, D.; Haridas, V. J. Am. Chem. Soc. 1997, 119, 2777-2783) or top-bottom-bound 1:1 (Garcia-Tellado, F.; Goswami, S.; Chang, S.K.; Geib, S.J.; Hamilton, A.D. J. Am. Chem. Soc. 1990, 112, 7393-7394) co-crystals.