1114808-95-5 Usage
Description
2-BROMO-3-(TRIFLUOROMETHYL)BENZALDEHYDE, also known as BRN 1231885 or Clearon, is a distinctive organic compound with the molecular formula C8H4BrF3O. It is a member of the benzaldehydes group, which are characterized by an aldehyde group attached to a benzene ring. This substance is a colorless to pale yellowish fluid with a strong odor and is not soluble in water. Due to its potential health risks if inhaled or comes into contact with skin, it is important to handle this chemical with care.
Uses
Used in Pharmaceutical Industry:
2-BROMO-3-(TRIFLUOROMETHYL)BENZALDEHYDE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Plastics Industry:
In the plastics industry, 2-BROMO-3-(TRIFLUOROMETHYL)BENZALDEHYDE is utilized as a chemical intermediate for the production of specific types of plastics. Its incorporation can enhance certain properties of the final plastic products, such as durability or resistance to certain conditions.
Used in Synthetic Fibers Industry:
2-BROMO-3-(TRIFLUOROMETHYL)BENZALDEHYDE is also used as a chemical intermediate in the synthesis of synthetic fibers. Its presence in the manufacturing process can contribute to the fibers' specific characteristics, such as strength, flexibility, or resistance to wear and tear.
Check Digit Verification of cas no
The CAS Registry Mumber 1114808-95-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,4,8,0 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1114808-95:
(9*1)+(8*1)+(7*1)+(6*4)+(5*8)+(4*0)+(3*8)+(2*9)+(1*5)=135
135 % 10 = 5
So 1114808-95-5 is a valid CAS Registry Number.
1114808-95-5Relevant articles and documents
Assessment of the regioselectivity in the condensation reaction of unsymmetrical o-phthaldialdehydes with alanine
D'Hollander, Agathe C.A.,Westwood, Nicholas J.
supporting information, p. 224 - 239 (2017/12/08)
One approach for the synthesis of isoindolinones, a privileged bioactive heterocyclic core structure, involves a condensation reaction of o-phthaldialdehydes with a suitable nitrogen-containing nucleophile. This fascinating reaction is revisited here in the context of the use of o-phthaldialdehydes that contain additional substituents in the aromatic ring leading to a detailed analysis of the regioselectivity of the reaction. Eleven monosubstituted o-phthaldialdehydes were synthesised and reacted with alanine. The regioselectivity observed across the eleven substrates led to the design of a disubstituted substrate that reacted with very high control. A gram-scale reaction followed by esterification gave one major regioisomer in high yield. In addition, the regioselectivity observed on reaction of two novel monodeuterated substrates led to an increased mechanistic understanding.
