1114809-02-7

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-3-chloro-2-fluorobenzaldehyde is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties. It plays a crucial role in the production of medications that target a wide range of health conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 6-Bromo-3-chloro-2-fluorobenzaldehyde is utilized as an intermediate for the synthesis of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Dye Production:
6-Bromo-3-chloro-2-fluorobenzaldehyde is also used in the production of dyes. Its chemical properties make it suitable for creating a variety of dyes with different color characteristics, which can be applied in various industries such as textiles, plastics, and printing inks.
Used in Organic Compounds Synthesis:
As a versatile building block in organic synthesis, 6-Bromo-3-chloro-2-fluorobenzaldehyde is used in the synthesis of other organic compounds. Its unique structure allows for the creation of new compounds with specific properties, which can be applied in various fields, including materials science, chemical research, and industrial applications.
It is important to handle and store 6-Bromo-3-chloro-2-fluorobenzaldehyde with care, as it may have hazardous properties if not properly managed. Proper safety measures should be taken to ensure the safe use of 6-BROMO-3-CHLORO-2-FLUOROBENZALDEHYDE in various applications.

Upstream product

• 60811-18-9 2-chloro-5-bromofluorobenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1186334-61-1 4-bromo-7-chloro-1H-indazole 
• 1360621-07-3 3-(3-bromo-6-chloro-2-formylphenoxy)-5-chlorobenzonitrile 
• 1034474-19-5 3-chloro-5-{[5-chloro-1-(1H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1H-indazol-4-yl]oxy}benzonitrile 
• 1360621-09-5 3-[3-(N'-benzhydrylidene-hydrazino)-6-chloro-2-dimethoxymethylphenoxy]-5-chlorobenzonitrile 
• 1360621-10-8 C₄₂H₃₄ClN₅O₃ 
• 1360621-11-9 C₄₁H₃₆Cl₂N₆O₅ 
• 1360621-12-0 C₃₆H₂₈Cl₂N₆O₃ 
• 1360621-13-1 C₄₈H₄₁Cl₂N₉O₅ 
• 1360621-08-4 C₁₆H₁₂BrCl₂NO₃ 

Relevant academic research and scientific papers

EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS

The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. For Formula I compounds X1, X2, X3, X4, X5, X6, Q, L1, L2, Y, R1, R2, R3, R4, R5, R6, R7, R8 and rings A, B and C are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4e and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5

The disclosure is directed to methods of treatment using compounds of Formula (I).

BENZOXABOROLE COMPOUNDS AND FORMULATIONS THEREOF

A benzoxaborole formulation composition including a benzoxaborole, a non-ionic surfactant, or a non-ionic and ionic surfactant mixture, and a carrier is described herein. At least one of the non-ionic surfactant, the non-ionic and ionic surfactant mixture

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)

The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

Process development and large-scale synthesis of MK-6186, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV

A new synthetic route has been developed to drug candidate 1, a second-generation NNRTI being developed as a potential treatment of HIV. Regiocontrol in a key alkylation step was achieved by selective N-alkylation of hydrazone 13. After a deprotection and cyclisation sequence, 1 was isolated in six steps in 35% overall yield from readily available starting materials.

BRIDGED, BICYCLIC HETEROCYCLIC OR SPIRO BICYCLIC HETEROCYCLIC DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF

Compounds of formula A: Formula (1) pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.