1114889-20-1Relevant academic research and scientific papers
Aldol-type reaction of a 4-pyrone: a straightforward approach to 4-pyrone-containing natural products
Sengoku, Tetsuya,Takemura, Takuma,Fukasawa, Emi,Hayakawa, Ichiro,Kigoshi, Hideo
, p. 325 - 328 (2009)
A straightforward approach to 4-pyrone-containing natural products has been developed, which includes an aldol-type reaction between 2,6-diethyl-3,5-dimethyl-4-pyrone and aldehydes. The counter cation of the carbanion of the pyrone was found to play an im
Total synthesis and biological evaluation of auripyrones A and B
Hayakawa, Ichiro,Takemura, Takuma,Fukasawa, Emi,Ebihara, Yuta,Sato, Natsuki,Nakamura, Takayasu,Suenaga, Kiyotake,Kigoshi, Hideo
, p. 1077 - 1092 (2013/01/15)
The total synthesis of auripyrones was achieved by using a novel aldol-type reaction of γ-pyrone as a key step. From this synthetic work, we have established the stereostructure and absolute configuration of auripyrone B. Furthermore, the cytotoxicities o
Total synthesis of auripyrones A and B and determination of the absolute configuration of auripyrone B
Hayakawa, Ichiro,Takemura, Takuma,Fukasawa, Emi,Ebihara, Yuta,Sato, Natsuki,Nakamura, Takayasu,Suenaga, Kiyotake,Kigoshi, Hideo
supporting information; experimental part, p. 2401 - 2405 (2010/06/17)
(Figure Presented) The winner takes it aldol: The total synthesis of auripyrones A and B was achieved using a diastereoselective aldol-type reaction with 2, 6-diethyl-3, 5-dimethyl-4-pyrone as a key step. The stereostructure and absolute configura-tion of auripyrone B has also been determined.
