111500-53-9Relevant academic research and scientific papers
Rapid and cheap synthesis of benzimidazoles via intermittent microwave promotion: A simple and potential industrial application of air as oxidant
Mao, Zhengzhou,Wang, Zhaoyang,Li, Jingning,Song, Xiumei,Luo, Yufen
, p. 1963 - 1977 (2010)
Using inexpensive KI as the catalyst in the presence of ambient air, benzimidazoles were synthesized from aromatic aldehydes and o-phenylenediamine with excellent yields via intermittent microwave irradiation without reflux equipment. The synthesis process was mild and only needed only a short reaction time (7-10min). As a simple example of the utilization of molecular oxygen under mild conditions, this method provides a novel way to synthesize benzimidazoles. The industrial synthesis of benzimidazoles may be realized by a cycle of microwave irradiation. Copyright
