1115338-99-2Relevant articles and documents
Synthesis and in-vitro activity of new 1β-methylcarbapenem derivatives as antibacterial agents
Jung, Myung-Ho,Joon, Hee Hong,Cho, Jung-Hyuck,Oh, Chang-Hyun
experimental part, p. 780 - 786 (2009/04/07)
The synthesis of a new series of 1β-methylcarbapenems having pyrrolidine and piperidine moieties is described. Their in-vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. A particular compound III b having an oxime-pyrrolidine moiety showed the most potent antibacterial activity.