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(6S,3R,3aR,6aR)-6-(tosyloxy)-hexahydrofuro[3,2-b]furan-3-yl acetate is a complex chemical compound that features an acetate ester with a tosylate group attached to a six-membered ring containing a furan and a tetrahydrofuran moiety. (6S,3R,3aR,6aR)-6-(tosyloxy)-hexahydrofuro[3,2-b]furan-3-yl acetate is characterized by its unique molecular structure, which makes it a valuable intermediate in the synthesis of complex organic molecules.

111554-46-2

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111554-46-2 Usage

Uses

Used in Organic Synthesis:
(6S,3R,3aR,6aR)-6-(tosyloxy)-hexahydrofuro[3,2-b]furan-3-yl acetate is used as a reagent in organic synthesis for various reactions. The tosylate group acts as a good leaving group in nucleophilic substitution reactions, while the acetate group can be cleaved to yield a hydroxyl group. This dual functionality makes it a versatile building block for creating a wide range of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (6S,3R,3aR,6aR)-6-(tosyloxy)-hexahydrofuro[3,2-b]furan-3-yl acetate is used as a key intermediate in the development of new drugs. Its unique structure allows for the creation of novel molecular entities with potential therapeutic applications.
Used in Chemical Research:
(6S,3R,3aR,6aR)-6-(tosyloxy)-hexahydrofuro[3,2-b]furan-3-yl acetate is also utilized in chemical research as a model compound for studying reaction mechanisms and exploring new synthetic pathways. Its complex structure provides a challenging framework for chemists to develop innovative strategies and techniques in organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 111554-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,5,5 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 111554-46:
(8*1)+(7*1)+(6*1)+(5*5)+(4*5)+(3*4)+(2*4)+(1*6)=92
92 % 10 = 2
So 111554-46-2 is a valid CAS Registry Number.

111554-46-2Relevant academic research and scientific papers

Architectural Control of Isosorbide-Based Polyethers via Ring-Opening Polymerization

Saxon, Derek J.,Nasiri, Mohammadreza,Mandal, Mukunda,Maduskar, Saurabh,Dauenhauer, Paul J.,Cramer, Christopher J.,Lapointe, Anne M.,Reineke, Theresa M.

supporting information, p. 5107 - 5111 (2019/03/29)

Isosorbide is a rigid, sugar-derived building block that has shown promise in high-performance materials, albeit with a lack of available controlled polymerization methods. To this end, we provide mechanistic insights into the cationic and quasi-zwitterionic ring-opening polymerization (ROP) of an annulated isosorbide derivative (1,4:2,5:3,6-trianhydro-d-mannitol, 5). Ring-opening selectivity of this tricyclic ether was achieved, and the polymerization is selectively directed toward different macromolecular architectures, allowing for formation of either linear or cyclic polymers. Notably, straightforward recycling of unreacted monomer can be accomplished via sublimation. This work provides the first platform for tailored polymer architectures from isosorbide via ROP.

Practical and scalable synthesis of isosorbide derivatives containing an active amine group

Li, Zhiwei,Hu, Qiulong,Kang, Shaoying,Li, Jiangsheng,Li, Heping,Xiong, Xingyao

, p. 215 - 218 (2018/05/26)

The synthesis of two derivatives of isosorbide containing an amine group, 6-amino-6-deoxy-O-3-methyl-isosorbide and 6-amino-O-3-benzoyl-6-deoxy-isosorbide, has been achieved. These compounds provide scope for the introduction of additional groups via thei

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