1115941-35-9Relevant academic research and scientific papers
Enzymatic approach to cascade synthesis of bis(indolyl)methanes in pure water
Fang, Ke,Fu, Yajie,He, Xinyi,Hu, Yi,Lu, Zeping,Xu, Huajin
, p. 10848 - 10853 (2020)
A mild, efficient, and green protocol was developed for the synthesis of bis(indolyl)methanes catalyzed by lipase TLIM through the cascade reactions of indole with aldehydes in pure water. This methodology offers many superiorities such as excellent yields, wide substrate range, simple procedure, reusable and minimal amount of catalyst, and the ability to be scaled up.
CuBr-catalyzed selective oxidation of N-azomethine: Highly efficient synthesis of methine-bridged bis-indole compounds
Yang, Jianguo,Wang, Zhijing,Pan, Fuyou,Li, Yongmin,Bao, Weiliang
experimental part, p. 2975 - 2978 (2010/09/06)
An efficient CuBr catalyzed cleavage of C-N bonds in the oxidative cross-dehydrogenative-coupling (CDC) of N-benzyl amines with indoles mediated by tert-butyl hydroperoxide (TBHP) was reported. A series of methine-bridged bis-indole derivatives were successfully synthesized under the optimized reaction conditions.
