111595-98-3Relevant academic research and scientific papers
Discovery and synthesis of methyl 2,5-dimethyl-4-[2- (phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogues: The first examples of a new class of calcium channel activator
Baxter,Dixon,Ince,Manners,Teague
, p. 2739 - 2744 (1993)
Methyl 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate, FPL 64176 (1), is the first example of a new class of calcium channel activator (CCA) that does not act on any of the well-defined calcium channel modulator receptor sites, as typif
An extremely short synthesis of benzoylpyrrole-type calcium channel activators
Dalton, Christopher R.,Kane, John M.,Rampe, David
, p. 5713 - 5716 (2007/10/02)
Friedel-Crafts acylation of methyl 2,5-dimethylpyrrole-3-carboxylate with 2-chloromethylbenzoyl chloride generated the corresponding 4-(2-chloromethylbenzoyl)pyrrole which was reacted in situ with benzene and aluminum chloride to yield the novel calcium c
