111663-00-4Relevant academic research and scientific papers
Synthesis and X-ray Analysis of a Sulfur Dioxide Analog of Triamterene
Cruz, Angeles de la,Goya, Pilar,Paez, Juan Antonio,Martinez-Ripoll, Martin
, p. 629 - 632 (2007/10/02)
The synthesis and X-ray analysis of a sulfur dioxide analog of the diuretic agent triamterene, namely 4,7-diamino-1-methyl-6-phenylpyrazinothiadiazine 2,2-dioxide (2b), is reported.The compound is devoid of the diuretic properties found in o
Pteridine Analogues; Synthesis and Physico-Chemical Properties of 7-Oxopyrazinothiadiazine 2,2-Dioxides
Goya, Pilar,Paez, Juan Antonio
, p. 121 - 124 (2007/10/02)
Condensation of diaminothiadiazine 1,1-dioxides 1 or 8 with α-keto acid esters affords 7-oxopyrazinothiadiazine 2,2-dioxides 2-4 and 9.Further chemical transformations yield 6-substituted derivatives.The structures of the newly synthesized c
