1116670-22-4Relevant academic research and scientific papers
Organocatalytic asymmetric inverse-electron-demand aza-Diels-Alder reaction of N-sulfonyl-1-aza-1,3-butadienes and aldehydes
Han, Bo,Li, Jun-Long,Ma, Chao,Zhang, Shan-Jun,Chen, Ying-Chun
supporting information; experimental part, p. 9971 - 9974 (2009/05/07)
(Chemical Equation Presented) Water is crucial for high transformation efficiency in the title reaction catalyzed by the α,α- diphenylprolinol derivative 1. Excellent stereoselectivities were observed for a broad spectrum of substrates (see scheme; TMS = trimethylsilyl, Tos = p-toluenesulfonyl). A diverse range of chiral piperidine derivatives and other valuable compounds can be prepared from the hemiaminal products.
