111669-20-6

Basic information

• Product Name: 2-chloro-4,6-di(1-pyrrolidinyl)-1,3,5-triazine
• Synonyms: 2-chloro-4,6-di(1-pyrrolidinyl)-1,3,5-triazine
• CAS NO: 111669-20-6
• Molecular Formula: C₁₁H₁₆ClN₅
• Molecular Weight: 253.73124
• Mol File: 111669-20-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-chloro-4,6-di(1-pyrrolidinyl)-1,3,5-triazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4,6-di(1-pyrrolidinyl)-1,3,5-triazine(111669-20-6)
• EPA Substance Registry System: 2-chloro-4,6-di(1-pyrrolidinyl)-1,3,5-triazine(111669-20-6)

Safety Data

• Hazardous Substances Data: 111669-20-6(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 108-77-0 1,3,5-trichloro-2,4,6-triazine 

Downstream Products

• 35953-92-5 2-phenyl-4,6-di(pyrrolidin-1-yl)-1,3,5-triazine 

Relevant articles and documents

PROTON CONDUCTING COMPOUND AND PROTON CONDUCTING POLYMER

Provided is a proton-conducting compound which provides proton conductivity without humidification and is suitable for electrochemical device materials such as solid electrolytes for fuel cells and electrolytes for batteries. Provided also is a proton-conducting polymer. The proton-conducting compound is composed of a melamine compound salt obtained from a melamine compound represented by the following formula (1) and a Bronsted acid and the proton-conducting polymer is obtained by homopolymerizing or copolymerizing the melamine compound salt. In formula (1), R1, R2, R3, R4, and R5 each is independently an alkyl group, an aryl group, an alkenyl group, a heterocyclic group, or a hydrogen atom; at least one of them is a group other than hydrogen; R2 and R3 or R4 and R5 may join together to form a heterocyclic structure; and the alkyl group, the aryl group, the alkenyl group, or the heterocyclic group may have a substituent. A melamine compound salt wherein R1 is CH2=CR6-CO-O(CH2)n- polymerizes to yield a proton-conducting polymer. In this particular R1 group, R6 is hydrogen or an alkyl group and n is an integer equal to or larger than 1.

Synthesis and aromatase-inhibitory activity of imidazolyl-1,3,5-triazine derivatives

Triamino-substituted 1,3,5-triazine derivatives were synthesized and tested for inhibitory activities against the aromatase of human placental microsomes and the cytochrome P450 side chain cleavage of cholesterol (P450(SCC)) of pig adrenal mitochondria. The compounds having imidazolyl and tertiary amino groups as substituents in the 1,3,5-triazine ring showed significant aromatase-inhibitory activity. Among them, compounds 17, 23, 26, 27 and 28 were more active than the reference compound, CGS 16949A. The inhibitory activities of these compounds against P450(SCC) were much weaker than their aromatase-inhibitory activities. These compounds may be regarded as selective aromatase inhibitors.