1116690-51-7

Basic information

• Product Name: (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone
• Synonyms: (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone
• CAS NO: 1116690-51-7
• Molecular Weight: 370.402
• Mol File: 1116690-51-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone(1116690-51-7)
• EPA Substance Registry System: (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone(1116690-51-7)

Safety Data

• Hazardous Substances Data: 1116690-51-7(Hazardous Substances Data)

Upstream product

• 133427-08-4 H-imidazo[1,2-α]pyridine-8-carboxylic acid 
• 121-44-8 triethylamine 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 1116691-46-3 imidazo[1,2-α]pyridine-8-carbonyl chloride hydrochloride 
• 1116691-47-4 1-(2,4-difiuorophenethyl)piperazine hydrochloride 

Downstream Products

• 1116690-60-8 (3-chloroimidazo[1,2-α]pyridin-8-yl)(4-(2,4-difluorophenethyl)piperazin-1-yl)methanone 
• 1116691-25-8 (4-(2,4-difluorophenethyl)piperazin-1-yl)(imidazo[l,2-α]pyridin-8-yl)methanone hydrochloride 

Relevant articles and documents

Identification of fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia

A series of fused bicyclic heterocycles was identified as potent and selective 5-HT2A receptor antagonists. Optimization of the series resulted in compounds that had improved PK properties, favorable CNS partitioning, good pharmacokinetic properties, and significant improvements on deep sleep (delta power) and sleep consolidation.