111705-52-3

Basic information

• Product Name: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (R)-
• CAS NO: 111705-52-3
• Molecular Formula: C23H23NO
• Molecular Weight: 329.442
• Mol File: 111705-52-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (R)-(111705-52-3)
• EPA Substance Registry System: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (R)-(111705-52-3)

Safety Data

• Hazardous Substances Data: 111705-52-3(Hazardous Substances Data)

Upstream product

• 111721-37-0 R-N-Tritylmethioninol 
• 111705-50-1 [(R)-4-Hydroxy-3-(trityl-amino)-butyl]-dimethyl-sulfonium; iodide 

Downstream Products

• 111769-27-8 (R)-3-aminotetrahydrofuranyl tosylate 

Relevant articles and documents

Application of N-Tritylmethionine in the Preparation of Heterocycles of Biological and Synthetic Interest

Treatment of the methylsulfonium salts of the corresponding N-tritylmethionine derivatives with sodium hydride or potassium tert-butoxide provides the heterocycles N-trityl-L-homoserine lactone (3), (S)- and (R)-3-(N-tritylamino)tetrahydrofuran (7a, 7b), (S)-1-hydroxy-3-(N-tritylamino)-2-pyrrolidinone (14), (S)-4-(N-tritylamino)-1,2-oxazinan-3-one (15), (S)-3-(N-tritylamino)-2-pyrrolidone (23), (S)-1-tert-butyloxycarbonylamino-3-(N-tritylamino)-2-pyrrolidone (27), and (S)-2-methyl-4-(N-tritylamino)-1,2-oxazinan-3-one (18).Methylation of 14 and 15 yields (S)-1-methoxy-3-(N-tritylamino)-2-pyrrolidone (17) and 18, respectively.The stereochemistry of compounds 3, 7a, and 17 has been determined by X-ray crystal structure analysis.