111735-81-0Relevant articles and documents
Novel cyclopropyl β-amino acid analogues of pregabalin and gabapentin that target the α2-δ protein
Schwarz, Jacob B.,Gibbons, Sian E.,Graham, Shelley R.,Colbry, Norman L.,Guzzo, Peter R.,Le, Van-Duc,Vartanian, Mark G.,Kinsora, Jack J.,Lotarski, Susan M.,Li, Zheng,Dickerson, Melvin R.,Su, Ti-Zhi,Weber, Mark L.,El-Kattan, Ayman,Thorpe, Andrew J.,Donevan, Sean D.,Taylor, Charles P.,Wustrow, David J.
, p. 3026 - 3035 (2007/10/03)
As part of a program aimed at generating compounds with affinity for the α2-δ subunit of voltage-gated calcium channels, several novel β-amino acids were prepared using an efficient nitroalkane-mediated cyclopropanation as a key step. Depending
