111742-14-4

Basic information

• Product Name: H-ALA-VAL-OME HCL
• Synonyms: L-ALANYL-L-VALINE METHYL ESTER HYDROCHLORIDE;H-ALA-VAL-OME HCL;(S)-methyl 2-((S)-2-aminopropanamido)-3-methylbutanoate hydrochloride;REF DUPL: H-Ala-Val-OMe HCl
• CAS NO: 111742-14-4
• Molecular Formula: C₉H₁₈N₂O₃*ClH
• Molecular Weight: 238.71
• Mol File: 111742-14-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: H-ALA-VAL-OME HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-ALA-VAL-OME HCL(111742-14-4)
• EPA Substance Registry System: H-ALA-VAL-OME HCL(111742-14-4)

Safety Data

• Hazardous Substances Data: 111742-14-4(Hazardous Substances Data)

Upstream product

• 95083-31-1 Boc-L-alanyl-L-valine methyl ester 
• 72-18-4 L-valine 

Relevant articles and documents

Antimicrobial toxicity studies of ionic liquids leading to a 'hit' MRSA selective antibacterial imidazolium salt

Imidazolium salts can be classed as surfactants, detergents, ionic liquids, reagents, catalysts or solvents. A study of the toxicity and ecotoxicity of these salts yields valuable information for their use as pharmaceuticals as well as impact on the environment. Our approach to screen a series of chiral imidazolium salts for toxicity to bacteria and fungi, including clinical pathogen strains, has led to the identification of a 'hit' MRSA selective antimicrobial compound. Preliminary structure-activity-relationship (SAR) information (required position of l-phenylalanine and l-valine group) is also elucidated within this first generation of compounds. Conversely, most of the imidazolium salts were nontoxic (IC95 > 2 mM) to the 12 fungi strains and 8 bacteria strains screened, and we propose that they are suitable candidates for 'green chemistry' applications. Ecotoxicity studies (Biodegradation ISO 14593 'CO2 Headspace Test') of two bromide ionic liquids containing l-phenylalanine residues indicate that these ionic liquids passed the test (>60% in 28 days) and classed as readily biodegradable.