111752-08-0

Basic information

• Product Name: 2-(2-Azidoethyl)-1,3-dioxolane
• Synonyms: 2-(2-Azidoethyl)-1,3-dioxolane;3-Azidopropionaldehyde Cyclic Ethylene Acetal;Azidoethyldioxolane
• CAS NO: 111752-08-0
• Molecular Formula: C₅H₉N₃O₂
• Molecular Weight: 143
• Product Categories: Heterocycles;Miscellaneous Reagents;Heterocycles, Miscellaneous Reagents
• Mol File: 111752-08-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 25 °C(Press: 0.1 Torr)
• Appearance: /
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 2-(2-Azidoethyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Azidoethyl)-1,3-dioxolane(111752-08-0)
• EPA Substance Registry System: 2-(2-Azidoethyl)-1,3-dioxolane(111752-08-0)

Safety Data

• Hazardous Substances Data: 111752-08-0(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Upstream product

• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 83665-55-8 2-(2-iodoethyl)-1,3-dioxolane 

Downstream Products

• 5754-35-8 2-[1,3]dioxolan-2-yl-ethylamine 
• 1392508-00-7 C₂₂H₃₁N₅O₇S 
• 1392508-10-9 C₂₂H₃₁N₅O₆S 
• 1392508-18-7 C₂₁H₂₉N₅O₆S 
• 1392508-26-7 C₂₁H₂₈ClN₅O₆S 
• 1392508-34-7 C₂₁H₂₈FN₅O₆S 
• 1428318-63-1 C₁₃H₁₄FN₃O₂ 
• 1198769-42-4 1-(2-(1,3-dioxolan-2-yl)ethyl)-5-iodo-4-phenyl-1H-1,2,3-triazole 
• 1085704-79-5 1-(2-(1,3-dioxolan-2-yl)ethyl)-4-(4-methoxyphenyl)-1H-1,2,3-triazole 

Relevant articles and documents

Synthetic studies towards N-substituted 3-vinyl-4-piperidineacetic acid derivatives

The synthesis and full characterization of two new (E)-2-butenyl)-5-amino-2-pentenoates, (Z)-4-[N-(3-buten-1-yl)benzamido]-2-buten-1-ol, and (Z)-1-chloro-4-[N-(3-buten-l-yl)benzamido]-2-butene are reported. These were designed as substrates for a projected thermal ene cyclization leading to the N-substituted 3-vinyl-4-piperidineacetic acid scaffold. Although conditions for this ene-cyclization have not yet been uncovered, the ease of preparation of these ene-cyclization substrates gives promise for their future use.

Palladium and copper-supported on charcoal: A heterogeneous multi-task catalyst for sequential Sonogashira-Click and Click-Heck reactions

This paper describes the development of one-pot sequential Sonogashira-Click and Click-Heck reactions by using Pd-Cu/C as a heterogeneous multi-task catalyst for the synthesis of heterocyclic structures. Details of the optimization studies and the substrate scope are discussed. These methodologies allow the preparation of functionalized triazoles in simple experimental conditions with inexpensive reagents.

Reusable and highly active supported copper(i)-NHC catalysts for Click chemistry

Immobilised [Cu(NHC)] catalysts are reported for the preparation of 1,2,3-triazoles. In addition to showing outstanding catalytic activity, the catalyst systems are easy to prepare and can be recycled many times.