111758-82-8 Usage
General Description
7-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YLAMINE HYDROCHLORIDE is a chemical compound that is also known as Droxidopa hydrochloride. It is a synthetic precursor of norepinephrine and is used in the treatment of symptomatic neurogenic orthostatic hypotension (NOH). NOH is a condition in which a person's blood pressure drops significantly when they stand up or change positions, resulting in symptoms such as dizziness, lightheadedness, and fainting. Droxidopa hydrochloride works by increasing the levels of norepinephrine in the body, which helps to improve blood pressure and reduce symptoms of NOH. It is available in the form of oral capsules and is typically used as a part of a comprehensive treatment plan for NOH under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 111758-82-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,7,5 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 111758-82:
(8*1)+(7*1)+(6*1)+(5*7)+(4*5)+(3*8)+(2*8)+(1*2)=118
118 % 10 = 8
So 111758-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO.ClH/c1-13-9-6-5-8-3-2-4-11(12)10(8)7-9;/h5-7,11H,2-4,12H2,1H3;1H
111758-82-8Relevant articles and documents
Substituted Bicyclic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands
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Page/Page column 32, (2012/05/20)
Substituted bicyclic carboxamide and urea compounds corresponding to formula (I) processes for the preparation thereof, pharmaceutical compositions containing these compounds, and a method of using these compounds for the treatment and/or inhibition of pain and other conditions mediated at least in part via the vanilloid receptor 1.
