111765-99-2Relevant articles and documents
Synthesis and Analgesic Properties of N-Substituted trans-4a-Aryldecahydroisoquinolines
Zimmerman, Dennis M.,Cantrell, Buddy E.,Swartzendruber, John K.,Jones, Noel D.,Mendelson, Laura G.,et al.
, p. 555 - 560 (2007/10/02)
A respresentative series of N-substituted derivatives of the morphine-based trans-4a-aryldecahydroisoquinoline were synthesized and evaluated for opioid analgesic activities.Compounds with potent analgesic activity and high affinities for the μ and κ opio