111771-12-1

Basic information

• Product Name: 2-FLUORO-6-IODOBENZOYL CHLORIDE 97
• Synonyms: 2-FLUORO-6-IODOBENZOYL CHLORIDE 97;2-Fluoro-6-iodobenzoyl chloride 97%
• CAS NO: 111771-12-1
• Molecular Formula: C₇H₃ClFIO
• Molecular Weight: 284.451
• Product Categories: Benzoic acid;Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 111771-12-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 267.945 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.956 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00791mmHg at 25°C
• Refractive Index: n20/D 1.5910(lit.)
• CAS DataBase Reference: 2-FLUORO-6-IODOBENZOYL CHLORIDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-6-IODOBENZOYL CHLORIDE 97(111771-12-1)
• EPA Substance Registry System: 2-FLUORO-6-IODOBENZOYL CHLORIDE 97(111771-12-1)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 111771-12-1(Hazardous Substances Data)

Usage

General Description

2-Fluoro-6-iodobenzoyl Chloride 97% is a specialized chemical compound, often used in organic synthesis. It has a fluorine atom and an iodine atom attached to a benzene ring, along with a carbonyl chloride group, which characterizes it as an acyl chloride. The '97%' indicates that the substance is 97% pure, meaning it contains very few impurities. However, this chemical is highly reactive, corrosive, and can cause burns and eye damage, so it must be handled with extreme caution. 2-FLUORO-6-IODOBENZOYL CHLORIDE 97 is generally used in a laboratory setting by researchers or technicians.

InChI:InChI=1/C7H3ClFIO/c8-7(11)6-4(9)2-1-3-5(6)10/h1-3H

Upstream product

• 111771-08-5 2-fluoro-6-iodobenzoic acid 

Downstream Products

• 1299473-11-2 (2R)-2-(2-{[(4aR,5R)-4a-cyclopropyl-1-(4-fluorophenyl)-5-hydroxy-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}-6-fluorophenyl)-2-fluoroethanamide 
• 1299474-40-0 (2R)-2-(2-{[(4aR,5R)-4a-cyclopropyl-1-(4-fluorophenyl)-5-hydroxy-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethynyl}-6-fluorophenyl)-2-fluoroethanamide 
• 1299474-39-7 (2R)-2-fluoro-2-(2-fluoro-6-iodophenyl)ethanamide 
• 1299474-38-6 (2R)-2-fluoro-2-(2-fluoro-6-iodophenyl)ethanoic acid 
• 1299474-37-5 (2R)-2-fluoro-2-(2-fluoro-6-iodophenyl)-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylacetamide 
• 1299474-36-4 2-(2-fluoro-6-iodophenyl)-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylacetamide 
• 1261782-26-6 (2-fluoro-6-iodophenyl)acetic acid 
• 1261826-29-2 ethyl (2-fluoro-6-iodophenyl)acetate 
• 146014-66-6 methyl 2-fluoro-6-iodobenzoate 
• 1293912-40-9 (Z)-N'-((2-fluoro-6-iodobenzoyl)oxy)acetimidamide 
• 1293284-60-2 2-fluoro-6-(pyrimidin-2-yl)benzoic acid 
• 1293284-62-4 methyl-2-fluoro-6-(pyrimidin-2-yl)benzoate 
• 1293284-61-3 methyl 2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 1293285-18-3 3-fluoro-2-(3-methyl-1,2,4-oxadiazol-5-yl)benzoic acid 

Relevant articles and documents

Palladium-Catalyzed Domino Heck/C-H Activation/Decarboxylation: A Rapid Entry to Fused Isoquinolinediones and Isoquinolinones

A new palladium-catalyzed tandem cyclization of various alkene-tethered aryl iodides has been presented. In this protocol, o-bromobenzoic acids are employed as coupling parters to achieve the insertion of aromatic rings by the cleavage of C(sp2)-Br and decarboxylation, thus assembling various dibenzoisoquinolinediones and dibenzoisoquinolinones. In addition, a seven-membered ring can be constructed by the use of 8-bromo-1-naphthoic acid. Notably, this approach enables regioselective product formation and features broad substrate scope.

Palladium-Catalyzed Amination/Dearomatization Reaction of Indoles and Benzofurans

This report describes a palladium-catalyzed dearomatization and amination tandem reaction of 2,3-disubstituted indoles and benzofurans via the Catellani strategy. This reaction provides a new method for the construction of amino-substituted indoline-fused cyclic and benzofuran spiro compounds in good yields. The reaction has broad functional group compatibility and substrate scope.

IODONIUM SALT COMPOUND, PHOTOACID GENERATOR AND COMPOSITION CONTAINING THE SAME, AND METHOD FOR MANUFACTURING DEVICE

PROBLEM TO BE SOLVED: To provide an iodonium salt compound which can be used as a chemical amplification type photoacid generator for resist and a photocationic polymerization initiator, has high sensitivity to an i-line at a wavelength of 365 nm, and has high solubility to an organic solvent and a resin. SOLUTION: A new iodonium salt compound is represented by the following iodonium salts 2, 5 and 10. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2019,JPOandINPIT