111787-91-8

Usage

Uses

Used in Organic Synthesis:
(2-METHYL-5-PHENYL-3-FURYL)METHANOL is used as a building block in organic synthesis for the creation of various chemical compounds.
Used in Pharmaceutical Industry:
(2-METHYL-5-PHENYL-3-FURYL)METHANOL is used as an intermediate in the production of pharmaceuticals due to its potential pharmacological activities, including its anti-inflammatory and analgesic properties.
Used in Agrochemical Industry:
(2-METHYL-5-PHENYL-3-FURYL)METHANOL is utilized in the development of agrochemicals, contributing to its role as a building block in the synthesis of various agro-related compounds.
Used in Fine Chemicals Production:
(2-METHYL-5-PHENYL-3-FURYL)METHANOL is employed in the production of fine chemicals, highlighting its importance in the field of organic chemistry.
Used in Perfumery and Fragrance Industry:
(2-METHYL-5-PHENYL-3-FURYL)METHANOL is used as a fragrance ingredient in the formulation of perfumes and fragrances, capitalizing on its pleasant odor.

InChI:InChI=1/C12H12O2/c1-9-11(8-13)7-12(14-9)10-5-3-2-4-6-10/h2-7,13H,8H2,1H3

Upstream product

• 29113-64-2 ethyl 2-methyl-5-phenylfuran-3-carboxylate 
• 70-11-1 α-bromoacetophenone 
• 52313-46-9 ethyl 2-acetyl-4-oxo-4-phenylbutanoate 
• 175276-57-0 5-phenyl-2-methyl-3-furoyl chloride 

Downstream Products

• 321309-42-6 2-methyl-5-phenylfuran-3-carbaldehyde 

Relevant academic research and scientific papers

Photochemical Alkene Isomerization for the Synthesis of Polysubstituted Furans and Pyrroles under Neutral Conditions

A photochemical approach to polysubstituted heterocycles using UV-induced alkene isomerization is described. The method allows for the synthesis of disubstituted furans and pyrroles under mild and neutral conditions and also provides access to a class of trisubstituted furans pertinent to natural-product synthesis. The method has broad functional-group tolerance and many richly decorated heterocycles have been prepared incorporating functional groups that are unstable under Br?nsted and Lewis acidic conditions.

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound represented by the following formula (I), which has a glucagon antagonistic action and is useful for the prophylaxis or treatment of diabetes and the like, a compound represented by wherein ring A is an optionally substituted benzene ring and the like; Y is a nitrogen atom and the like; X is -O- and the like; R4 is a hydrogen atom and the like; R5 and R6 are each independently a hydrogen atom and the like; R1 is an optionally substituted hydrocarbon group and the like; R2 is a hydrogen atom and the like; and R3 is -(CH2)3-COOH and the like, or a salt thereof.

Halomethyl derivatives of 2-phenylfurans in the Arbuzov and Michaelis-Becker reactions

The α-phenyl substituent in 3-(chloromethyl)furan, nonconjugated with the reaction center, does not hinder the nucleophilic attack of phosphite anion under conditions of the Michaelis-Becker reaction, while in the isomer with a conjugated phenyl substituent the halogen atom is attacked under the same conditions. Reaction of the latter with trimethyl phosphite yields the corresponding phosphonate. Phosphorylation of 5-(bromomethyl)-2-phenylfuran derivatives containing acceptor substituents in the β-position of the furan ring with trimethyl phosphite in the presence of amyl alcohol as proton donor involves no attack of the phosphite on the halogen atom and the products of the classic Arbuzov reaction are formed.