111793-95-4Relevant academic research and scientific papers
Asymmetric Synthesis with Chiral β-Lactams. α-Substituted Aromatic α-Amino Acids and Their Derivatives through Highly Stereoselective Alkylations
Ojima, Iwao,Chen, Hauh-Jyun C.,Nakahashi, Kazuaki
, p. 278 - 281 (2007/10/02)
A novel route to optically pure α-alkylated aromatic α-amino acids and their dipeptide derivatives was developed through the asymmetric alkylation at the C-3 position of a chiral β-lactam 1 followed by the reductive cleavage of the alkylated β-lactams 2.T
NEW APPROACHES TO THE ASYMMETRIC SYNTHESIS OF NON-PROTEINOGENIC α-AMINO ACIDS AND DIPEPTIDES THROUGH CHIRAL β-LACTAM INTERMEDIATES
Ojima, Iwao,Chen, Hauh-Jyun C.,Qiu, Xiaogang
, p. 5307 - 5318 (2007/10/02)
Novel and effective routes to optically pute aromatic α-amino acids, α-methyl-α-amino acids and their derivatives including dipeptides are developed via homochiral β-lactams which are obtained through asymmetric cycloadditions of ketenes to imines.
