111801-75-3Relevant academic research and scientific papers
Ring-closing metathesis for the synthesis of 2H- and 4H-chromenes
Van Otterlo, Willem A.L.,Ngidi, E. Lindani,Kuzvidza, Samuel,Morgans, Garreth L.,Moleele, Simon S.,De Koning, Charles B.
, p. 9996 - 10006 (2007/10/03)
Six 4H-chromenes were synthesized from substituted phenols using vinylstannylation and ring-closing metathesis (RCM) as key steps. In addition, a different approach involving amongst other steps, an aryl allyl isomerization and RCM afforded a set of seven 2H-chromenes from phenolic precursors.
Sequential isomerization and ring-closing metathesis: Masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles
Van Otterlo, Willem A. L.,Ngidi, E. Lindani,De Koning, Charles B.
, p. 6483 - 6486 (2007/10/03)
The use of an aryl allyl ether and an arylallyl group as masked vinyl ether and 1-propenylphenyl groups for ring-closing metathesis (RCM) leading to the synthesis of benzo-fused heterocycles was demonstrated by using a ruthenium-mediated isomerization followed by a ruthenium-mediated RCM reaction. This resulted in the syntheses of a variety of products including two substituted benzo[1,4]dioxins, a naphtho[2,3-b][1,4]dioxin, a 2H-chromene and a benzo[b]furan.
