1118073-50-9Relevant academic research and scientific papers
Synthesis of 1-amino-1H-indole-3-carboxylates by copper(I)-catalyzed intramolecular amination of aryl bromides
Melkonyan, Ferdinand,Topolyan, Artyom,Yurovskaya, Marina,Karchava, Alexander
experimental part, p. 5952 - 5956 (2009/05/27)
A simple route to various N-substituted 1-amino-1H-indole-3-carboxylates by use of copper(I)-catalyzed intramolecular N-arylation has been established. For the preparation of N-monosubstituted and N-unsubstituted derivatives, the cyclization of Boc-protected enehydrazines and subsequent deprotection were applied. Furthermore, 1-alkoxyindole-3-carboxylates can be synthesized by use of the same protocol Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
