111830-77-4

Basic information

• Product Name: 10-O-Methylprotosappanin B
• Synonyms: 10-O-Methylprotosappanin B;7,8-Dihydro-6-(hydroxymethyl)-10-methoxy-6H-dibenz[b,d]oxocin-3,7,11-triol stereoisomer
• CAS NO: 111830-77-4
• Molecular Formula: C17H18O6
• Molecular Weight: 318.32122
• Mol File: 111830-77-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 616.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.399±0.06 g/cm3(Predicted)
• PKA: 9.09±0.40(Predicted)
• CAS DataBase Reference: 10-O-Methylprotosappanin B(CAS DataBase Reference)
• NIST Chemistry Reference: 10-O-Methylprotosappanin B(111830-77-4)
• EPA Substance Registry System: 10-O-Methylprotosappanin B(111830-77-4)

Safety Data

• Hazardous Substances Data: 111830-77-4(Hazardous Substances Data)

Usage

General Description

10-O-Methylprotosappanin B is a natural compound found in the heartwood of Caesalpinia sappan Linn, a plant in the legume family. It is an alkaloid with potential anti-inflammatory and antioxidant properties. Studies have shown that 10-O-Methylprotosappanin B exhibits inhibitory effects on nitric oxide (NO) production and the expression of inflammatory mediators, making it a potential candidate for the treatment of inflammatory diseases. Additionally, the compound has shown promise in protecting against oxidative stress and free radical damage, indicating its potential as a therapeutic agent for conditions related to oxidative stress. Its biological activities suggest that 10-O-Methylprotosappanin B may hold potential for the development of new pharmaceuticals for the treatment of inflammatory and oxidative stress-related diseases.

Upstream product

• 111852-38-1 C₂₀H₂₂O₆ 

Relevant articles and documents

Homoisoflavonoids and Related Compounds. V. A Novel Dibenzoxocin Derivative from Caesalpinia sappan L.

A novel dibenzoxocin derivative, 7,8-dihydro-10-methoxy-3,7,11-trihydroxy-6H-dibenzoxocin-7-methanol was isolated from Sappan Lignum, the dried heartwood of Caesalpinia sappan L.The chemical structure was established on the basis of the spectrometric data and the chemical interrelation with protosappanin B (7,8-dihydro-3,7,10,11-tetrahydroxy-6H-dibenzoxocin-7-methanol).Keywords - Caesalpinia sappan; Sappan Lignum; Leguminosae; heartwood; dibenzoxocin derivative; 10-O-methylprotosappanin B; (1)H-(1)H difference NOE spectrum