111836-69-2Relevant academic research and scientific papers
Heterocyclic Systems Containing Bridgehead Nitrogen Atom: Synthesis of Imidazo-benzothiazoles and Quinoxalinoimidazobenzothiazoles
Mohan, Jag,Anjaneyulu, G. S. R.,Arora, D. R.
, p. 183 - 185 (2007/10/02)
2-Amino-6-t-butyl-4,5,6,7-tetrahydrobenzothiazole (II), obtained from 4-t-butylcyclohexanone and thiourea, on condensation with α-haloketones in benzene gives the ketones III which undergo cyclization in hot ethanol to give imidazobenzothiazoles (IV).Compounds IV have also been obtained in one-step by heating II with α-haloketones in ethanol.II on treatment with 2,3-dichloroquinoxaline and chloroacetic acid yields in one-step quinoxalinoimidazobenzothiazole (V) and imidazobenzothiazol-3(2H)-one (VI), respectively.The anthelmintic, antibacterial and antifungal activities of IV and V have been evaluated.
