111844-24-7 Usage
Description
H-GLY-ARG-GLY-ASP-D-SER-PRO-OH is a peptide chain composed of the amino acids glycine (GLY), arginine (ARG), aspartate (ASP), D-serine (D-SER), and proline (PRO). This peptide is significant in biochemical and pharmacological studies due to its potential applications in drug development, protein engineering, and in vitro studies of protein-protein interactions. The presence of D-serine in the sequence suggests that this peptide may have important functional and structural roles in biological systems, as D-amino acids are often found in biologically active peptides and have been extensively researched in pharmacology.
Uses
Used in Biochemistry and Pharmaceutical Research:
H-GLY-ARG-GLY-ASP-D-SER-PRO-OH is used as a research tool for studying protein-protein interactions and developing new drugs. Its unique sequence, including D-serine, makes it a valuable candidate for exploring the functional roles of D-amino acids in biological systems.
Used in Drug Development:
H-GLY-ARG-GLY-ASP-D-SER-PRO-OH is used as a potential therapeutic agent in drug development. Its presence in biologically active peptides and the extensive research on D-amino acids in pharmacology suggest that this peptide may have therapeutic applications.
Used in Protein Engineering:
H-GLY-ARG-GLY-ASP-D-SER-PRO-OH is used as a component in protein engineering to create novel proteins with specific functions or improved properties. The peptide's unique sequence and the presence of D-serine make it a promising candidate for engineering proteins with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 111844-24-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,8,4 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 111844-24:
(8*1)+(7*1)+(6*1)+(5*8)+(4*4)+(3*4)+(2*2)+(1*4)=97
97 % 10 = 7
So 111844-24-7 is a valid CAS Registry Number.
InChI:InChI=1/C22H37N9O10/c23-8-15(33)28-11(3-1-5-26-22(24)25)18(37)27-9-16(34)29-12(7-17(35)36)19(38)30-13(10-32)20(39)31-6-2-4-14(31)21(40)41/h11-14,32H,1-10,23H2,(H,27,37)(H,28,33)(H,29,34)(H,30,38)(H,35,36)(H,40,41)(H4,24,25,26)/t11?,12?,13-,14?/m1/s1
111844-24-7Relevant articles and documents
Fibrinogen-coated particles for therapeutic use
-
, (2008/06/13)
The invention provides a particle comprising fibrinogen bound on the surface of an albumin matrix, wherein said particle is capable of coaggregation with platelet, and of aggregation in a solution containing soluble fibrinogen at a concentration of soluble fibrinogen not capable by it self of formation of a clot upon activation by thrombin.
Triurethane-protected guanidines and triflyldiurethane-protected guanidines: New reagents for guanidinylation reactions
Feichtinger, Konrad,Sings, Heather L.,Baker, Tracy J.,Matthews, Kenneth,Goodman, Murray
, p. 8432 - 8439 (2007/10/03)
New guanidinylation reagents are reported. These reagents consist of N,N',N''-tri-Boc-guanidine (1) and N,N',N''-tri-Cbz-guanidine (2), which allow for the facile conversion of alcohols to substituted guanidines. A series of arginine analogues were synthesized via condensation of a primary or secondary alcohol with the guanidinylation reagents 1 or 2, under Mitsunobu conditions, to produce protected alkylated guanidines. In addition, an extended study of the previously reported reagents N,N'-di-Boc-N''- triflylguanidine (3) and N,N'-di-Cbz-N''-triflylguanidine (4) is presented. The triflyldiurethane-protected guanidine 3 was utilized to guanidinylate primary and secondary amines under mild conditions with high yield in both solution and on solid phase.
