111862-90-9Relevant academic research and scientific papers
Microwave-assisted synthesis of α-aminophosphine oxides
Tripolszky, Anna,Bálint, Erika,Keglevich, Gy?rgy
, p. 345 - 348 (2019/03/07)
Aminophosphine oxides and bis(phosphinoylmethyl)amines were synthesized by the microwave (MW)-assisted Kabachnik-Fields reaction of primary amines, paraformaldehyde and secondary phosphine oxides. The bisphosphines obtained after deoxygenation of the bis(phosphinoymethyl)amine derivatives were utilized in the synthesis of cyclic transition metal complexes.
A Convenient Synthetic Route to N-Aryl and N-Alkylamino(alkyl) Phosphonates and Phosphine Oxides
Couture, A.,Deniau, E.,Woisel, P.,Grandclaudon, P.
, p. 2483 - 2486 (2007/10/02)
A variety of phosphorylated N-aryl and N-alkyl N-formyl and N-tert-butoxycarbonylaminomethyl derivatives have been efficiently prepared by treatment of the corresponding chloromethyl derivatives with a trialkyl phosphite or an alkyl diphenylphosphinite.These bifunctional compounds may be deprotonated with LDA and further submitted to electrophilic substitution.An acidic treatment of the resulting compounds gives rise to a range of N-aryl and N-alkylamino(alkyl) phosphonates and phosphine oxides.
