1119-75-1

Basic information

• Product Name: 2-chloroethyl stearate
• Synonyms: 2-chloroethyl stearate;Octadecanoic acid,2-chloroethyl ester
• CAS NO: 1119-75-1
• Molecular Formula: C₂₀H₃₉ClO₂
• Molecular Weight: 346.98
• Mol File: 1119-75-1.mol

Chemical Properties

• Boiling Point: 425.2°C at 760 mmHg
• Flash Point: 205.7°C
• Appearance: /
• Density: 0.928g/cm³
• Vapor Pressure: 1.96E-07mmHg at 25°C
• Refractive Index: 1.454
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-chloroethyl stearate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloroethyl stearate(1119-75-1)
• EPA Substance Registry System: 2-chloroethyl stearate(1119-75-1)

Safety Data

• Hazardous Substances Data: 1119-75-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H39ClO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h2-19H2,1H3

Upstream product

• 112-92-5 1-octadecanol 
• 107-06-2 1,2-dichloro-ethane 
• 112-76-5 Stearoyl chloride 
• 107-07-3 2-chloro-ethanol 
• 57-11-4 stearic acid 

Downstream Products

• 25234-57-5 O-stearoylcholine chloride 

Relevant articles and documents

Esterifications of carboxylic acids and alcohols catalyzed by Al 2(SO4)3 · 18H2O under solvent-free condition

Esterifications of equimolar mixture of carboxylic acids and alcohols can be effectively catalyzed by Al2(SO4)3 · 18H2O under solvent-free condition. The esterification catalyzed by Al2(SO4)3 · 18H2O is a promising green method thanks to no need of organic solvent, no pollution, no causticity and ease to handle after reaction. This catalyst is of a low toxicity (usually it is used as purifying agent for drinking water), low-cost compound and is easily separated from the reaction mixture by simple filtration. Moreover, the catalyst can be recycled for the further esterification and the conversion does not evidently decrease.

Sustained release pharmaceutical compositions

The present invention relates to a pharmaceutical composition comprising a salt of quaternary ammonium of an acid drug in the form of a suspension or an emulsion, suitable for parenteral administration and providing a sustained release of the drug. In one preferred embodiment, the present invention is directed to a long term sustained release composition for parenteral administration, comprising a salt of heparin or low molecular weight heparin in an emulsion with a salt of acylcholine, for the prevention and treatment of venous thrombosis and pulmonary embolism.

Palladium(II)-mediated oxidation of alcohols using 1,2-dichloroethane as Pd(0) reoxidant

The oxidation of primary and secondary, saturated, allylic or benzylic, alcohols is carried out in 1,2-dichloroethane at reflux using catalytic amounts of both PdCl2 and Adogen 464 in the presence of an excess of sodium carbonate. High selectivities are obtained from saturated and benzylic, secondary alcohols. Primary alcohols afford mixtures of aldehydes and esters. The migration of the double bond of α,β-unsaturated alcohols is a competing reaction. It is clearly shown that 1,2-dichloroethane reoxidizes the Pd(0) species.