1119471-86-1Relevant articles and documents
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
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Paragraph 00111, (2021/08/06)
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). (I) Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
ATR inhibitors and application thereof in medicines
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Paragraph 0097-0100, (2021/05/29)
The invention relates to novel compounds represented by a formula (I). The novel compounds have ATR regulating activity. The invention also relates to a preparation method of the compounds and a pharmaceutical composition containing the compounds.
Diversity-oriented synthesis of substituted pyrazolo-[4,3-d][1,2,3]triazin-4-ones
Meibom, Daniel,Bauser, Marcus,Meier, Heinrich,Schneider, Dirk,Svenstrup, Niels,Haebich, Dieter
experimental part, p. 71 - 91 (2009/05/07)
An efficient synthesis of 3,7-disubstituted 3,5-dihydro-4H-pyrazolo-[4,3-d][1,2,3]triazin-4-ones (2), especially suited for late-stage decoration, is described. Diverse 3-benzyl analogs were obtained by amidation-cyclization in one pot and various pyrazol