111949-32-7

Basic information

• Product Name: (5S,6S)-5,6-dimethoxy-2-(1-naphthyl)-2-phenyl-1,3-dioxa-2-silacycloheptane
• Synonyms: (5S,6S)-5,6-dimethoxy-2-(1-naphthyl)-2-phenyl-1,3-dioxa-2-silacycloheptane
• CAS NO: 111949-32-7
• Molecular Weight: 380.516
• Mol File: 111949-32-7.mol

Chemical Properties

• CAS DataBase Reference: (5S,6S)-5,6-dimethoxy-2-(1-naphthyl)-2-phenyl-1,3-dioxa-2-silacycloheptane(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,6S)-5,6-dimethoxy-2-(1-naphthyl)-2-phenyl-1,3-dioxa-2-silacycloheptane(111949-32-7)
• EPA Substance Registry System: (5S,6S)-5,6-dimethoxy-2-(1-naphthyl)-2-phenyl-1,3-dioxa-2-silacycloheptane(111949-32-7)

Safety Data

• Hazardous Substances Data: 111949-32-7(Hazardous Substances Data)

Upstream product

• 24679-72-9 (2S,3S)-2,3-dimethoxy-1,4-butanediol 
• 7751-39-5 dichloro(1-naphthyl)phenylsilane 

Relevant articles and documents

Asymmetric Synthesis of Silicon Compounds Using Chiral 5,6-Dimethoxy-1,3,2-dioxasilacycloheptane Derivatives

Asymmetric synthesis of silicon compounds was achieved in high optical yield by the substitution reaction of some chiral 5,6-dimethoxy-1,3,2-dioxasilacycloheptane derivatives with organometallic reagents followed by lithium aluminium hydride reduction.The

Asymmetric Synthesis of Organosilicon Compounds Using a C2 Chiral Auxiliary

Optically active silanes were synthesized by a novel asymmetric synthesis which involved the diastereoselective ring-opening reaction of 1,3-dioxa-2-silacycloheptanes bearing a C2 chiral auxiliary with Grignard reagents, followed by a lithium aluminum hydride (LiAlH4) reduction. (R)-Ethylmethylphenylsilane and (R)-methylphenylpropylsilane were derived in 93%ee and 98%ee, respectively. The preparation of the other optical silanes is also described. The maximum rotations of some of them have been determined by 1H NMR and/or capillary GC methods. A mechanism for a diastereoselective ring-opening reaction is proposed based on the stereochemical results.