1119700-53-6Relevant articles and documents
Trimethylsilyl iodide mediated one-pot synthesis of 2-allyl-2H-chromenes
Padhi, Birakishore,Reddy, D. Srinivas,Mohapatra, Debendra K.
, p. 542 - 547 (2015)
A new and efficient metal-free trimethylsilyl iodide (TMSI) catalyzed one-pot synthesis of 2-allyl-2H-chromenes has been developed that takes place under mild conditions. The synthesis proceeds through a Wittig reaction by using (triphenylphosphoranylidene)acetaldehyde to form an ohydroxycinnamaldehyde derivative followed by a tandem isomerization and C-O and C-C bond-forming reactions. The procedure was carried out at room temperature in the presence of 20 mol-% of TMSI and allyltrimethylsilane in tetrahydrofuran (THF) and provided the 2-allyl-2H-chromenes in good to excellent yields.
Organocatalytic asymmetric Michael/hemiacetalization/acyl transfer reaction of α-nitroketones with o-hydroxycinnamaldehydes: Synthesis of 2,4-disubstituted chromans
Maity, Rajendra,Pan, Subhas Chandra
supporting information, p. 1598 - 1608 (2018/03/08)
An organocatalytic asymmetric cascade Michael/hemiketalization/acyl transfer reaction between o-hydroxycinnamaldehydes and α-nitroketones is developed. Prolinol TMS ether catalyst in combination with benzoic acid was found to be the most effective for this reaction which proceeds through an equilibrium of lactols to provide a single diastereomer of enantiopure 2,4-disubstituted chromans.
An efficient carbene-catalyzed access to 3,4-dihydrocoumarins
Zeitler, Kirsten,Rose, Christopher A.
supporting information; experimental part, p. 1759 - 1762 (2009/08/07)
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