1119899-50-1

Basic information

• Product Name: (5-cyano-4-methylthiophen-2-yl)boronic acid
• Synonyms: (5-cyano-4-methylthiophen-2-yl)boronic acid;2-Cyano-3-methylthiophene-5-boronic acid;5-Cyano-4-methylthiophene-2-boronic acid
• CAS NO: 1119899-50-1
• Molecular Formula: C₆H₆BNO₂S
• Molecular Weight: 167
• Mol File: 1119899-50-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (5-cyano-4-methylthiophen-2-yl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (5-cyano-4-methylthiophen-2-yl)boronic acid(1119899-50-1)
• EPA Substance Registry System: (5-cyano-4-methylthiophen-2-yl)boronic acid(1119899-50-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 1119899-50-1(Hazardous Substances Data)

Usage

General Description

"(5-cyano-4-methylthiophen-2-yl)boronic acid" is a specialized chemical compound that uniquely contains boronic acid. (5-cyano-4-methylthiophen-2-yl)boronic acid contains several notable structures including a methyl group (-CH3), a thiophen ring, a cyano functional group (-CN) and boronic acid (-B(OH)2). Thiophen is a heterocyclic compound, consisting of a five-member ring with four carbon atoms and one sulfur atom. The 5-cyano-4-methylthiophen-2-yl boronic acid compound is likely to possess distinct chemical and physical properties, including reactivity, due to the presence of these different functional groups. Potential applications could include use in scientific research, such as organic synthesis, or in the production of pharmaceuticals or other chemical products. However, the exposures or releases from this compound could also result in environmental or health impacts to be managed during its handling, storage, and use.

Upstream product

• 55406-13-8 3-methylthiophene-2-carbonitrile 

Downstream Products

• 1142946-52-8 5-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-methylthiophene-2-carbonitrile 
• 1142947-55-4 5-(2-(3-(4-methylpiperazin-1-yl)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-methylthiophene-2-carbonitrile 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.