112029-98-8

Basic information

• Product Name: 4-Hydroxymethyl-1-methylpyrazole
• Synonyms: 1-Methyl-1H-pyrazole-4-methanol;4-Hydroxymethyl-1-methylpyrazole;1H-pyrazole-4-methanol, 1-methyl-;(1-methyl-1H-pyrazol-4-yl)methanol(SALTDATA: FREE);(1-Methyl-1H-pyrazol-4-yl...;(1-methyl-4-pyrazolyl)methanol;(1-methylpyrazol-4-yl)methanol
• CAS NO: 112029-98-8
• Molecular Formula: C₅H₈N₂O
• Molecular Weight: 112.13
• Mol File: 112029-98-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 244 °C
• Flash Point: 101 °C
• Appearance: /
• Density: 1.16
• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C
• PKA: 14.10±0.10(Predicted)
• CAS DataBase Reference: 4-Hydroxymethyl-1-methylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxymethyl-1-methylpyrazole(112029-98-8)
• EPA Substance Registry System: 4-Hydroxymethyl-1-methylpyrazole(112029-98-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 112029-98-8(Hazardous Substances Data)

Usage

General Description

4-Hydroxymethyl-1-methylpyrazole is an organic chemical compound with the molecular formula C5H8N2O. It is categorized under the pyrazole family, specifically a methylpyrazole due to the inclusion of the methyl (-CH3) group. Its molar mass is 112.13 g/mol. This chemical structure consists of a pyrazole ring, which is a heterocyclic aromatic organic compound with two nitrogen atoms. In accordance with drug discovery and development, it might function as a basic building block. Care should be taken while handling this compound as it may pose certain hazards under specific conditions. Detailed scientific analyses are essential to determine its precise properties and potential applications in various fields.

InChI:InChI=1/C5H8N2O/c1-7-3-5(4-8)2-6-7/h2-3,8H,4H2,1H3

Upstream product

• 100852-80-0 diethyl 1-methylpyrazole-3,5-dicarboxylate 
• 85290-80-8 ethyl 1-methylpyrazole-4-carboxylate 
• 25016-11-9 1-methylpyrazole-4-carbaldehyde 

Downstream Products

• 735241-98-2 4-(chloromethyl)-1-methyl-1H-pyrazole 
• 154312-86-4 4-(chloromethyl)-1-methyl-1H-pyrazole hydrochloride 
• 762237-02-5 4-(bromomethyl)-1-methyl-1H-pyrazole 
• 760951-49-3 4-[(ethylthio)methyl]-1-methyl-1H-pyrazole 

Relevant articles and documents

ATG7 INHIBITORS AND THE USES THEREOF

Disclosed are chemical entities which are compounds of formula (I) : or a pharmaceutically acceptable salt thereof, wherein R1, R2, and Ra have the values described herein. Chemical entities according to the disclosure can be useful as inhibitors of ATG7. Further provided are pharmaceutical compositions comprising a chemical entity of the disclosure and methods of using the compositions in the treatment of cancer.

FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor.(Formula I) (I)

COMPOUNDS

Disclosed are compounds that inhibit Lp-PLA2 activity, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.