1120367-22-7Relevant academic research and scientific papers
Synthesis of Boc-amino tetrazoles derived from α-amino acids
Sureshbabu, Vommina V.,Naik, Shankar A.,Nagendra
experimental part, p. 395 - 406 (2009/06/06)
A simple route for the synthesis of Boc-protected tetrazole analogs of amino acids starting from Nα-Boc amino acids has been described. The [2 + 3] cycloaddition of Boc-α-amino nitrile and sodium azide in the presence of a catalytic amount of zinc bromide yielded the desired tetrazoles in good yields and purity. All the compounds obtained have been characterized by 1H and 13C-NMR and mass spectral studies. Copyright Taylor & Francis Group, LLC.
