112057-68-8

Upstream product

• 104701-87-3 (2S)-3-(tert-butyl-dimethyl-silyloxy)-2-methyl-propanal 
• 622-30-0 N-benzyl hydroxylalmine 
• 93454-85-4 (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropionic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 112057-65-5 (3R,4S,5R)-2-Benzyl-3-[(R)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-ethyl]-5-methyl-isoxazolidine-4-carboxylic acid benzyl ester 
• 112057-79-1 2-benzyl-4-benzyloxycarbonyl-3-[(2'-t-butyldimethylsilyloxy-1'-methyl)ethyl]-5-methylisoxazolidine 
• 115764-34-6 (3R,4S,5R)-3-((R)-2-Acetoxy-1-methyl-ethyl)-2-benzyl-5-methyl-isoxazolidine-4-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Application of the silicon-tether strategy for controlling the regioselectivity and diastereoselectivity of intramolecular nitrone cycloadditions for aminopolyol synthesis

Highly regioselective and diastereoselective intramolecular chiral nitrone cycloaddition reactions with a vinyl group tethered by a silicon atom have been developed as a general method for the synthesis of stereodefined amino polyols. This strategy featur

Amino acid derivatives, and their production

An amino acid derivative of the formula: STR1 wherein R1 is a protective group for hydroxyl, which is useful as an intermediate for production of antimicrobial agent.

A CHIRAL SYNTHESIS OF THE KEY INTERMEDIATE OF 1β -METHYLCARBAPENEM ANTIBIOTIC

The synthetic intermediate, (-)-(3S,4R)-3--4-azetidin-2-one (2), of 1β -methylcarbapenem antibiotic was synthesized from (S)-methyl 3-hydroxy-2-methylpropionate through the intermolecular nit