112064-22-9

Basic information

• Product Name: (2-methylphenyl)(4-pyridinyl)methanol
• Synonyms: (2-methylphenyl)(4-pyridinyl)methanol
• CAS NO: 112064-22-9
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.24842
• Mol File: 112064-22-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-methylphenyl)(4-pyridinyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methylphenyl)(4-pyridinyl)methanol(112064-22-9)
• EPA Substance Registry System: (2-methylphenyl)(4-pyridinyl)methanol(112064-22-9)

Safety Data

• Hazardous Substances Data: 112064-22-9(Hazardous Substances Data)

Usage

General Description

"(2-methylphenyl)(4-pyridinyl)methanol" is a compound with a molecular formula C13H13NO that consists of a 2-methylphenyl group and a 4-pyridinyl group attached to a methanol molecule. (2-methylphenyl)(4-pyridinyl)methanol is used in the field of organic chemistry for various synthetic applications. It may also have potential applications in pharmaceutical research, as the combination of the phenyl and pyridinyl groups could impart specific chemical and biological properties. Due to its unique structure, "(2-methylphenyl)(4-pyridinyl)methanol" could be of interest for further investigation and development in the field of medicinal chemistry and drug discovery.

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 529-20-4 2-methylphenyl aldehyde 
• 681160-67-8 2-((2-methylbenzyl)oxy)isoindoline-1,3-dione 
• 95-46-5 2-methylphenyl bromide 
• 21656-86-0 4-(2-methylbenzoyl)pyridine 
• 872-85-5 pyridine-4-carbaldehyde 

Downstream Products

• 36995-46-7 4-[(2-methylphenyl)methyl]pyridine 
• 496056-24-7 4-(2-methyl-benzyl)-piperidine 
• 21656-86-0 4-(2-methylbenzoyl)pyridine 

Relevant articles and documents

Reductive arylation of aliphatic and aromatic aldehydes with cyanoarenes by electrolysis for the synthesis of alcohols

An electroreductive arylation reaction of aliphatic and aromatic aldehydes as well as ketones with electro-deficient (hetero)arenes is described. A variety of cyano(hetero)arenes and carbonyl compounds, especially aliphatic aldehydes, have been examined, providing secondary and tertiary alcohols in moderate to good yields. Mechanistic studies, including cyclic voltammetry (CV), electron paramagnetic resonance (EPR), and divided-cell experiments, support the generation of aliphatic ketyl radicals and persistent heteroaryl radical anions via cathodic reduction followed by radical-radical cross-coupling.

Bifunctional Oxo-Tethered Ruthenium Complex Catalyzed Asymmetric Transfer Hydrogenation of Aryl N-Heteroaryl Ketones

A facile asymmetric transfer hydrogenation of ortho-substituted aryl N-heteroaryl ketones and non-ortho-substituted N-oxide of aryl N-heteroaryl ketones using a readily available oxo-tethered ruthenium complex as a catalyst and sodium formate as a hydrogen source in an aqueous solution has been discovered. A variety of chiral aryl N-heteroaryl methanols were obtained with up to 99.9% ee.

Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues: Synthesis and monoamine oxidase catalyzed bioactivation

Eighteen analogues of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were synthesized and evaluated as substrates of monoamine oxidase. In general, the flexible analogues, characterized by the presence of a methylene (or ethylene) bridge between the aryl/heteroaryl and tetrahydropyridyl moieties, were better substrates of the enzyme than the conformationally restricted MPTP. It is suggested that the increased oxidative activity of these flexible analogues reflects enhanced binding due to the ability of the C-4-aryl/heteroaryl substituent to gain access to a hydrophobic pocket within the substrate binding site.