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112076-61-6

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Product FOB Price Min.Order Supply Ability Supplier
Cholan-24-oic-2,2,4,4-d4acid, 3,12-dihydroxy-, (3a,5b,12a)-
Cas No: 112076-61-6
No Data No Data 10000 Metric Ton/Month Henan Wentao Chemical Product Co., Ltd. Contact Supplier
7-Deoxycholic acid,-2,2,4,4-d4 CAS:112076-61-6 the cheapest price
Cas No: 112076-61-6
USD $ 15.0-18.0 / Kilogram 1 Kilogram 1000 Metric Ton/Day Hebei youze Biotechnology Co.,Ltd Contact Supplier
Deoxycholic-2,2,4,4-d4 Acid
Cas No: 112076-61-6
No Data No Data No Data Hangzhou Huarong Pharm Co., Ltd. Contact Supplier
Deoxycholic Acid-[d4]
Cas No: 112076-61-6
No Data No Data No Data SHANGHAI ZZBIO CO., LTD. Contact Supplier
Cholan-24-oic-2,2,4,4-d4acid, 3,12-dihydroxy-, (3a,5b,12a)-
Cas No: 112076-61-6
No Data No Data No Data Clearsynth Labs Limited Contact Supplier
DEOXYCHOLIC-2,2,4,4-D4 ACID
Cas No: 112076-61-6
No Data No Data No Data Medical Isotopes, Inc. Contact Supplier

112076-61-6 Usage

Description

Deoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid (Item No. 20250) in the colon.1 It can be conjugated to glycine or taurine (Item No. 27031) to produce glycodeoxycholic acid (GDCA; Item No. 20274) or taurodeoxycholic acid (TDCA; Item No. 15935), respectively, in hepatocytes.1,2,3 DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; Item No. 16215) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v.1 It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM.4 Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.5 Increased serum DCA levels have been found in patients with colorectal cancer.6

Uses

Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound.

112076-61-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,12-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

1.2 Other means of identification

Product number -
Other names Deoxycholic acid-2,2,4,4-d4

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112076-61-6 SDS

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