112079-99-9Relevant academic research and scientific papers
ADDITION OF PHTHALIMIDONITRENE TO SUBSTITUTED INDOLES
Kumar, Perumal Raja
, p. 1257 - 1262 (2007/10/02)
The aziridine 2a obtained by the addition of phthalimidonitrene to N-phenylsulphonylindole was treated with methanolic potassium hydroxide to give desulphonated indole and quinazoline.The aziridine 2b and 2c derived from phthalimidonitrene and 2-methylindole or 2-phenylindole were treated with dimsyl anion to give 2-methylquinazoline and 2-phenylquinazoline.However the nitrene adducts 2d and 2e derived from 1,2,3,4-tetrahydrocarbazole and 1-oxo-1,2,3,4-tetrahydrocarbazole afford carbazole and 1-hydroxycarbazole under similar conditions.Hydrozinolysis of the nitrene adducts 2a, b, c, d and e regenerated the parent indole.
