112084-89-6Relevant academic research and scientific papers
Preparation of β-Keto Ester Acetals by Reaction of Ortho Esters with Ketene Silyl Acetals in the Presence of Titanium Tetrachloride
Collins, David J.,Choo, Gabrielyn Lee Poh,Obrist, Hans
, p. 617 - 622 (2007/10/02)
Reaction of 2-ethoxy-2-methyl-1,3-dioxolan (1c) with 1-methoxy-1-trimethylsilyloxyethene (4a) in dichloromethane in the presence of titanium tetrachloride gave 62percent of methyl 2-(2'-methyl-1',3'-dioxolan-2'-yl)acetate (5a).Similarly, reaction of (1c) with 1-methoxy-1-trimethylsilyloxyprop-1-ene (4b) afforded 73percent of methyl 2-(2'-methyl-1',3'-dioxolan-2'-yl)propanoate (5b).
