112093-50-2

Upstream product

• 140-29-4 phenylacetonitrile 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 112093-40-0 Phenyl-5 cyano-5 pentanoate d'ethyle 

Downstream Products

• 112093-43-3 Phenyl-6 tetrahydro-4,5,6,7 <3H>azepinone-2 
• 111742-89-3 6-(t-butoxycarbonylamino)-5-phenylhexanoic acid 
• 111742-90-6 6-tert-Butoxycarbonylamino-5-phenyl-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 111742-91-7 6-Amino-5-phenyl-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester; hydrochloride 
• 111820-54-3 (S)-2-((3S,6S)-1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid ethyl ester; hydrochloride 
• 111743-06-7 α-<(3S,6R)-3-<<(S)-1-(ethoxycarbonyl)-3-phenylpropyl>amino>2-oxo-6-phenylperhydroazepin-1-yl>acetic acid hydrochloride 
• 111743-02-3 (3S^*,6R^*)-3-azido-6-phenylperhydroazepin-2-one 
• 111742-95-1 (3S^*,6S^*)-3-azido-6-phenylperhydroazepin-2-one 
• 111743-12-5 tert-butyl α-<(3S^*,6S^*)-3-amino-2-oxo-6-phenylperhydroazepin-1-yl>acetate 
• 111743-04-5 tert-butyl α-<(3S^*,6R^*)-3-amino-2-oxo-6-phenylperhydroazepin-1-yl>acetate 
• 111743-03-4 tert-butyl α-<(3S^*,6R^*)-3-azido-2-oxo-6-phenylperhydroazepin-1-yl>acetate 
• 111820-50-9 (S)-2-((3S,6S)-1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid 
• 111742-85-9 (S)-2-((3S,6R)-1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino)-4-phenyl-butyric acid 
• 111821-30-8 t-butyl α-{3(S)-[1(S)-ethoxycarbonyl-3-phenylpropylamino]-2-oxo-6(S)-phenylperhydroazepin-1-yl}acetate 

Relevant academic research and scientific papers

Angiotensin-converting enzyme inhibitors. 2. Perhydroazepin-2-one derivatives

α-[(3S)-3-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2-oxo-6 or 7-phenylperhydroazepin-1-yl]acetic acids (monoester monoacids) and their dicarboxylic acids were synthesized, and their angiotensin-converting enzyme (ACE) inhibitory activities were eval

LACTAM DERIVATIVES AND THEIR USE AS HYPOTENSIVE AGENTS

Compounds of formula (I): STR1 (wherein R 1 and R 3 are organic groups, A is a direct bond,--CH 2--,--CH 2 CH. sub.2--,--CO--CH 2,--O--CH 2--or--S--CH 2--, B is lower alkylene and n is 1-3) are valuable hypotensive agents which may be prepared by a conden