112101-54-9

Basic information

• Product Name: Benzo[b]thiophene-5-carboxylic acid, 6,7-dihydro-2-(hydroxyphenylmethyl)-, methyl ester
• CAS NO: 112101-54-9
• Molecular Formula: C17H16O3S
• Molecular Weight: 300.378
• Mol File: 112101-54-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzo[b]thiophene-5-carboxylic acid, 6,7-dihydro-2-(hydroxyphenylmethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene-5-carboxylic acid, 6,7-dihydro-2-(hydroxyphenylmethyl)-, methyl ester(112101-54-9)
• EPA Substance Registry System: Benzo[b]thiophene-5-carboxylic acid, 6,7-dihydro-2-(hydroxyphenylmethyl)-, methyl ester(112101-54-9)

Safety Data

• Hazardous Substances Data: 112101-54-9(Hazardous Substances Data)

Upstream product

• 112101-62-9 methyl 2-benzoyl-6,7-dihydrobenzothiophene-5-carboxylate 
• 13414-95-4 4-keto-4,5,6,7-tetrahydrothianaphthene 
• 112101-59-4 methyl 6,7-dihydrobenzothiophene-5-carboxylate 
• 112101-60-7 methyl 4-oxo-4,5,6,7-tetrahydro-1-benzothiophene-5-carboxylate 
• 209535-91-1 4-Hydroxy-4,5,6,7-tetrahydro-benzo[b]thiophene-5-carboxylic acid methyl ester 

Downstream Products

• 112101-40-3 methyl 2-(1-imidazolylphenylmethyl)-6,7-dihydrobenzothiophene-5-carboxylate 
• 112101-41-4 sodium 2-(1-imidazolylphenylmethyl)-6,7-dihydrobenzothiophene-5-carboxylate 
• 119971-59-4 2-(1-imidazolylphenylmethyl)-4,5,6,7-tetrahydrobenzothiophene-5-carboxylic acid hydrochloride 
• 119971-61-8 methyl 2-(1-imidazolylphenylmethyl)-4,5,6,7-tetrahydrobenzothiophene-5-carboxylate 

Relevant articles and documents

Synthesis and Thromboxane Synthetase Inhibitory Activity of Di- or Tetrahydrobenzothiophenecarboxylic Acid Derivatives

1-Imidazolylalkyl-substituted di- or tetrahydrobenzothiophenecarboxylic acid derivatives and related compounds were synthesized from tetrahydrobenzothiophene derivatives (1 or 4) in order to study the structure-activity relationships of the inhibition of thromboxane A2 synthetase in vitro.Sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzothiophene-6-carboxylate (26) and 2-(1-imidazolylmethyl)-4,5,6,7-tetrahydrobenzothiophene-6-carboxylic acid hydrochloride (28) showed the most potent and specific activity in vitro and in vivo for thromboxane A2 synthetase inhibition.