112122-58-4Relevant articles and documents
Synthesis of Some New Substituted Mercaptotriazoles and Thiazolidones and Their Monoamine Oxidase Inhibitory and Anticonvulsant Properties
Husain, M. I.,Amir, Mohd,Singh, Eira
, p. 251 - 254 (2007/10/02)
A number of 4-aryl-5-aryloxymethyl-3-mercapto-1,2,4(H)-triazoles (IV) and 2-arylimino-3-aryloxyacetamido-4-thiazolidones (V) have been synthesized.Some of these compounds inhibit rat brain monoamine oxidase (MAO) in vitro at a final concentration of 1E-3 mol/litre, but are found to be inactive against pentylenetetrazole induced seizures in mice at a dose of 80 mg/kg.